Dapoxetine

What Is Dapoxetine?

Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation in men. It helps increase the time taken to ejaculate, enhancing overall sexual satisfaction.

History Of Dapoxetine 

Originally developed by the pharmaceutical company Eli Lilly, dapoxetine was designed as a fast-acting Selective Serotonin Reuptake Inhibitor (SSRI) for the treatment of premature ejaculation (PE). Initially, it was developed as an antidepressant, but was later used for treating PE due to its positive impact on ejaculation control. 

 In 2003, the rights to dapoxetine were sold to Johnson & Johnson, which further advanced its development. The following year, in 2004, Johnson & Johnson submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA), aiming to gain approval for its use specifically in the treatment of PE.

Dapoxetine Brand Name 

Dapoxetine is sold under various brand names, with Priligy being the most common. The other brand names of Dapoxetine include- Poxet, Duralast,  Dapoforce, and Dapotime. It is also available in combination with other medications such as Tadalafil and Sildenafil. 

Formulations

Dapoxetine is available as oral tablets. These are solid medications designed to be swallowed and absorbed through the digestive system. They contain active ingredients and inactive ingredients (binders, fillers, coatings). 

Medical Uses Of Dapoxetine 

Dapoxetine tablet uses include treating premature ejaculation (PE) in adult men aged 18 to 64. It enhances ejaculatory latency (time before ejaculation).

How Dapoxetine Works?

Dapoxetine increases serotonin activity in the nervous system, delaying the ejaculation reflex. This action helps in better control and reduces the stress or frustration associated with premature ejaculation.

Dapoxetine Dosages 

Dapoxetine is commonly available in tablet form and comes in 30 mg and 60 mg. 

The Dapoxetine Hydrochloride tablets 30 mg are recommended for beginners, and the higher dose, such as the Dapoxetine 60mg, may be prescribed if 30 mg is ineffective and well tolerated.

How To Take Dapoxetine?

• Take the tablet with a full glass of water.
• Can be taken with or without food.
• Take dapoxetine for premature ejaculation about 1 to 3 hours before planned sexual activity.
• Do not exceed one dose in 24 hours.

Dapoxetine Warnings

• Avoid alcohol while taking Dapoxetine.
• Not suitable for men with heart problems, liver disease, or psychiatric conditions.
• May cause dizziness, so avoid driving or operating machinery after use.
• Should not be combined with MAOIs, SSRIs, or nitrates.
• Not recommended for men over 65 years of age.
• Inform your doctor if you have a history of erectile dysfunction, low blood pressure, mania, bleeding, or blood clotting problems. 

Dapoxetine Side Effects

Common side effects of Dapoxetine tablets may include:- 

• Nausea
• Dizziness
• Headache
• Insomnia
• Fatigue

Serious but rare effects may include- 

• Fainting.
• Mood changes.
• Vision disturbances.

Seek medical help if any severe reaction occurs.

Dapoxetine Options At GTC Meds 

The Dapoxetine options available at GTC Meds include- 

Duratia 30 Mg

Vriligy 60 Mg. 

Dapoxetine Alternatives At GTC Meds

The effective alternatives of Dapoxetine treatment may include a combination of drugs containing –

• Tadalafil and Dapoxetine
• Sildenafil and Dapoxetine