Sildenafil

What Is Sildenafil?

Sildenafil is a prescription medication approved for the treatment of erectile dysfunction (ED) in men by improving blood flow to the penis. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors and works within 30 minutes of intake. 

History Of Sildenafil

Sildenafil was originally developed in the 1990s by Pfizer as a treatment for heart conditions like angina, discomfort caused by reduced blood flow to the heart muscle. However, during clinical trials, researchers observed an unexpected benefit: improved erections. Following this, Pfizer decided to market it as an Erectile dysfunction treatment. 

Sildenafil got its FDA approval in 1998 for erectile dysfunction, making it the first oral treatment of its kind.

Sildenafil Brand Name 

Sildenafil is sold under the brand name Viagra. It is also available in generic versions that offer the same benefits at more affordable prices, including-

• Cenforce.
• Revatio.
• Kamagra
• Aurogra
• Malegra 
• Fildena
• Cobra
• Sildigra.
• Suhagra
• Caverta.

Formulations

• Oral tablets – These are solid tablets that should be swallowed with water. 
• Sublingual tablets- These are taken by placing the medicine under the tongue where it dissolves and is absorbed into the blood. 
• Chewable tablets- These tablets are chewed and then swallowed by the patient. 
• Oral jelly- They offer a semisolid formulation that helps with resolving swallowing issues. 

Medical Uses Of Sildenafil

The Sildenafil tablet is prescribed for treating erectile dysfunction in men, a condition that causes inability to get and maintain an erection.  It is also approved for treating pulmonary arterial hypertension (PAH). This is a condition that is characterized by high blood pressure in the arteries of the lungs. 

How Sildenafil Works?

Sildenafil works by inhibiting the PDE5 enzyme, which breaks down cyclic GMP, a substance that helps relax smooth muscles and increase blood flow. By blocking PDE5, Sildenafil helps maintain cGMP levels. This helps in better blood flow in the body, promoting better erection. 

Sildenafil Dosages 

The Sildenafil tablet is available in the dosage strengths of 25mg, 50mg, 100mg, 150mg, and 200mg. Whereas, Sildenafil 25mg or 50mg is ideal for beginners, and higher strengths such as 200mg are recommended for severe cases. 

Always consult a healthcare provider to determine the appropriate dose for your condition.

How To Take Sildenafil?

• Take sildenafil 30 to 60 minutes before sexual activity.
• It can be taken with or without food; however, a high-fat meal may delay its effect.
• Do not take more than one dose in 24 hours.
• For PAH, it is usually taken 3 times daily. It is best to take this medicine at the same time every day. 
• Do not take the medicine after its expiry date. 

Sildenafil Warnings

• Before using sildenafil, inform your doctor if you:
  • Have heart problems, low blood pressure, or a recent stroke. 
  • Are allergic to Sildenafil. 
  • Are taking nitrate medications, as it can cause severe side effects. 
  • Have liver or kidney disease. 
  • Have vision or hearing issues. 
• Avoid using Sildenafil with alcohol or grapefruit juice. 
• Pregnant and lactating women should use Sildenafil for PAH only after consulting a doctor. 
• Individuals below the age of 18 years should not use Sildenafil without consulting a doctor. 
• Do not drive or use heavy machinery if you experience dizziness. 

Sildenafil Side Effects

Common side effects of Sildenafil that do not require any medical attention include-

• Diarrhea. 
• Sensitivity to light.
• Nausea.
• Headache.
• Nasal congestion. 
• Flushing. 
• Muscle pain. 
• Heartburn.

In severe cases, it can result in the following symptoms-

• Chest pain. 
• Fainting.
• Shortness of breath. 
• Painful erection lasting more than 4 hours. 
• Rash.
• Difficulty swallowing.

If any of these side effects appear, consult a doctor immediately. 

Sildenafil Options At GTC Meds 

The Sildenafil option available at GTC Meds includes-

• Fildena 100mg
• Cenforce 200mg
• Kamagra 100mg oral jelly
• Cenforce 150mg
• Cenforce 100mg
• Aurogra 100mg
• Kamagra 100mg 
• Malegra 200mg
• Cobra 120 Tablet
• Fildena 150 Mg
• Sildigra 100 Mg  
• Kamagra 100mg Chewable Tablet
• Tadalafil Black 80 Mg
• Fildena Super Active
• Cenforce 120mg
• Malegra 100mg
• Fildena Chewable Tablet 100 Mg
• cenforce 50mg
• Suhagra 100 Mg
• Silagra 100 Mg
• Fildena 50 Mg
• Fildena 120 Mg
• Cenforce Professional 100 Mg
• Cenforce 25mg
• Cenforce Soft 100 Mg
• Fildena 25 Mg
• Silditop 100 Mg Tablet
• Malegra Oral Jelly
• Fildena CT 50 Mg
• Sildigra XL Plus 150 Mg 
• Kamagra Gold 100 Mg
• Kamagra Effervescent 100 Mg 
• Vigora 100 Mg
• Cenforce 130mg
• Kamagra Polo 100 Mg 
• Caverta 100 Mg

Sildenafil Alternatives At GTC Meds

The Sildenafil alternative available at GTC Meds includes Vardenafil, Avanafil, Udenafil, and Tadalafil. They are both effective PDE5 inhibitors and work within 30 minutes of intake. Always consult a doctor before changing the medicine.